Articles

How to think about a nerve cross-section as a design space: geometry, selectivity proxies, and safe stimulation.

Article 16

The 2D nerve cross-section sandbox (electrodes, fields, constraints)

simulation · peripheral-nerve · electrodes

A 2D cross-section model is the highest-leverage starting point for the simulation roadmap. It is simple enough to run in the browser and intuitive enough to teach. It also captures the first-order truth: in many regimes, selectivity and recruitment are geometry problems.

What the sandbox should let you do

At minimum:

  • choose a nerve cross-section with fascicle layout,
  • place electrode geometries (cuff, FINE-like, intrafascicular, “regenerative zone”),
  • set stimulation parameters,
  • see field/recruitment proxies,
  • export/import settings.

What we can measure (early proxies)

We won’t claim perfect biophysics at v1. But we can compute useful proxies:

  • distance-weighted field magnitude within fascicles,
  • overlap metrics (how selectively are we targeting one fascicle vs others?),
  • threshold-like contours (relative, not absolute),
  • safety bounds (charge per phase and charge density estimates).

Why 2D is not “fake”

2D cross-sections are a legitimate way to build intuition and to test design strategies quickly. As we add complexity later, the 2D sandbox becomes the conceptual map.

References (starter)