BISC wireless subdural CMOS array

A mechanically flexible micro-ECoG chip that combines electrodes, signal processing, wireless data telemetry and wireless power on one CMOS substrate. Jung and colleagues’ Nature Electronics paper was published on 8 December 2025. The primary affiliations include Columbia University’s electrical engineering and computer science departments, with other US collaborators.

Physical sites versus channels

The chip has a 256 x 256 array: 65,536 recording electrodes. It can simultaneously record a selectable subset of up to 1,024 channels. These are different counts. The device does not stream all 65,536 sites at once in the reported configuration.

The paper reports 50 µm total thickness and placement below the dura. Figure 1 identifies titanium-nitride (TiN) electrodes. Full chip outline, contact dimensions and electrode pitch are not supplied by the abstract and captions used for this entry, so they are not inferred from the count or photographs.

Wireless system

The implant includes an analog front-end for recording and stimulation, an inductive wireless-power link, a bidirectional wireless transceiver and a controller. An external relay headstage provides power and communication outside the body, with an HDMI connection to a processor module. The processor is computer-controlled.

“Wireless implant” describes the link across the body boundary, not the absence of external equipment or cables. Figure 1’s stimulation circuitry does not, by itself, establish a therapeutic stimulation outcome.

What was shown

The abstract reports reliable chronic recordings for up to two weeks in pigs and two months in behaving non-human primates, covering somatosensory, motor and visual cortices. Those are the durations demonstrated here, not years of implant survival.

Figure 2 shows porcine somatosensory-evoked potentials recorded from 256 channels at 33.9 kS/s and decoding of stimulation location. Figure 3 shows a behaving non-human primate reaching to grab a wand, with cortical activity used to predict wrist velocity. That example also uses 256 channels at 33.9 kS/s. The maximum 1,024-channel capability should not be substituted for the actual subset used in each result.

Motor-feature prediction during a trained reach is not the same as a paralyzed person controlling an assistive device. No human implantation or clinical efficacy is demonstrated in the abstract and figures used here.

Limits and model status

This entry uses the peer-reviewed 2025 paper rather than treating the earlier preprint as a separate hardware device. It keeps physical electrode count, simultaneous channel capacity and example recording subset distinct.

No 3D model is added from the thickness and matrix count alone. The complete package outline, contact sizes, wireless-coil geometry and configuration-specific channel mapping remain outside the sources inspected for this entry. Chronic tissue and material reliability beyond the stated pig and primate durations are not established here.

Sources

• Jung T, Zeng N, et al. A wireless subdural-contained brain-computer interface with 65,536 electrodes and 1,024 channels. Primary abstract, author affiliations, 8 December 2025.
• Figure 1: implant and relay station. Circuit blocks, wireless link, TiN contacts and external equipment.
• Figure 2: porcine somatosensory recording.
• Figure 3: motor-cortex recording in a behaving non-human primate.

The full fabrication and implantation methods are not reproduced from the accessible abstract and captions.