Devices

16 x 16 gold-on-polyimide micro-ECoG array with 850 micrometer sites at 1250 micrometer pitch, in a titanium-housed implant with four Intan chips. 203 days in a Labrador, then intraoperative and short-term human motor-imagery decoding at Huashan Hospital. SIMIT with NeuroXess.

Catalog specification sheet - Cortical surface

SIMIT 256-channel high-density micro-ECoG (64 electrodes/cm2)

Record ID
BTSD-ACAD-0090
Reviewed
2026-10-09
Interface
ecog
Evidence stage
human

Independent, source-linked catalog sheet. Not a manufacturer-issued datasheet, regulatory decision or instructions for clinical use. Human evidence does not establish approval. Source-specific restrictions, conflicts and missing specifications are retained below.

SIMIT 256-channel high-density micro-ECoG (64 electrodes/cm2)

A cortical-surface array from Zhou Zhitao’s group at the Shanghai Institute of Microsystem and Information Technology (SIMIT, CAS) and Tao Hu’s team at NeuroXess, tested clinically at Huashan Hospital, Fudan University (Wu Zehan is a corresponding author). It is a different array from the NeuroXess 256-channel flexible ECoG, which the sources there describe with 3 mm pitch. Details are from the Advanced Science paper (2025, full text via Europe PMC) and SIMIT’s Chinese release.

Identity

FieldValue and source scope
DeviceµECoG array, flexible printed circuit, signal processing unit and titanium enclosure, with a decoding and device-control software stack [1][2]
OriginSIMIT with NeuroXess and Huashan Hospital [2]
Interface classCortical-surface array, mesh recording area [1]
Species studiedOne Labrador (male, about 18 months, 30 kg) for 203 days; human intraoperative and short-term trials [1]
Regulatory statusResearch; Huashan Hospital IRB approval KY2021-918; participants were tumor patients needing awake surgery [1]

Geometry and architecture

FieldValue and source scope
Electrode count256 channels, 16 x 16 [1]
Site diameter and pitch850 µm sites, 1250 µm apart; 64 electrodes/cm2, which the SIMIT release calls 64 times the density of clinical ECoG [1][2]
LayersUltrathin mesh recording area with thickened lead zones for robustness [1]
Implant electronicsFour Intan RHD2164 chips; flexible printed circuit; customized titanium enclosure, watertight and airtight [1]

Materials and fabrication

FieldValue and source scope
ProcessSandwich of gold in polyimide, adapted from the group’s earlier silk-enabled bioelectronics work [1]
Layers7 µm PI-2610 on a silicon wafer; Cr 50 angstrom and Au 150 nm by e-beam evaporation with lift-off; 13 µm PI encapsulation [1]
OpeningsAluminum etch mask, aluminum etched, oxygen plasma dry etch for site openings and perfusion holes [1]
ReleaseHydrofluoric acid etch from the wafer [1]
Pre-implant testMore than 95% of electrodes under 1 MΩ at 1 kHz; RMS noise under 2 µV in PBS [1]

Performance envelope

FieldValue and source scope
Canine stability203 days; electrode yield fell 5.49%; SNR stayed above 20 dB; real-time 3D motor decoding mean accuracy 0.84 [1][2]
DecodersLSTM and position-velocity Kalman filter on high-gamma power spectral density features; recalibration 5 to 7 minutes between sessions [1]
Human intraoperativeAfter 7 minutes of training the participant played ping-pong (1D, mean accuracy 0.90) and snake (2D) by brain signals [1]
Human short-termImplanted up to about 12 days; 19.87 h of training; center-out up to 1.13 bits/s, WebGrid up to 4.15 bits/s after interface changes [1][2]. The SIMIT release compares this with a 4.60 bits/s figure for a Neuralink participant; that comparison is the institute’s, not the paper’s
Density effectWithin a 2 x 2 cm area, higher electrode density improved decoding without more coverage [1]

Limits

Human follow-up is days, not months. Participant numbers beyond the quoted sessions and supplementary figures were not read. The “comparable to intracortical” language is the authors’ framing.

References

  1. Chronically Stable, High-Resolution Micro-Electrocorticographic Brain-Computer Interfaces for Real-Time Motor Decoding, Advanced Science (2025). DOI 10.1002/advs.202506663. Read through Europe PMC full text.
  2. SIMIT (Chinese), 上海微系统所在高通量柔性脑机接口临床实时运动解码方面取得进展, 15 September 2025.